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Of apples and potatoes: the Dutch lobby for the deregulation of cisgenesis

The voice of the Dutch Government has been loud and clear in Brussels on the issue of cisgenic plants. The Dutch have waged a sustained campaign to have new GM techniques – and in particular cisgenesis – excluded from EU GMO regulations. Several Dutch ministries, the Dutch Parliament, the Dutch Permanent Representation in Brussels, and Dutch MEPs have energetically pursued this goal. PDF of this case study.
 

Belgian show field of Dutch GM DuRPh potatoes
Belgian show field of Dutch GM DuRPh potatoes

The Dutch GM potato

So why is the Netherlands so focused on the regulatory status of cisgenesis? In short, the Dutch are hoping that cisgenic genetic engineering can make the Dutch plant breeding sector more competitive. The Netherlands is known for its considerable stake in the seed industry. The Dutch potato sector for example accounts for 60 per cent of global exports in seed potatoes.1 However, fears have been expressed in The Hague that the sector could lose its standing if competitors from other countries are able to use genetic modification, which consumer rejection has ruled out in the Netherlands.2

For this reason, the Dutch Government committed public research funding in 2005 to the development of a 'national GM potato'. Ten million euro was made available to Wageningen University to develop a GM potato that is resistant to late blight (Phytophthora infestans). The project – 'Durable Resistance to Phytophthora' (or DuRPh, which means 'dare' in Dutch) – 'stacks' three to five blight-resistant genes from wild varieties of potatoes, and then inserts them into commercial potato varieties.

Dutch Government policy is to cap public science funding at 50 per cent of a research project, requiring matching funding from the private sector. Yet in this case the Dutch potato sector refused to invest in the project, and the exceptional decision was taken to entirely finance the R&D of the GM cisgenic potato from public science coffers. A sizeable one-tenth of the DuRPh budget – one million euro – was allocated to communication with stakeholders and the public in order to overcome the anticipated resistance to the project.

However, there was an additional obstacle for project sponsors: European GM laws, which play a crucial role in facilitating consumer choice. If classified and labeled as a GMO, rejection by consumers and the potato processing industry would likely stymie the commercial success of the project. Having cisgenesis excluded from GM laws thus became a key objective for the Dutch Government.

Cisgenesis vs transgenesis: is the debate scientific or semantic?

The term 'cisgenesis' refers to the insertion of genes from the same or closely related species into a recipient plant, in contrast with transgenesis, whereby genes from another species are introduced. Wageningen University plant scientists Evert Jacobsen and Henk Schouten are considered the 'fathers' of cisgenesis; Schouten coined the term in 1999.3

Schouten and Jacobsen made their case for cisgenesis in the Nature Biotechnology journal in 2006, stating that “cisgenic plants are fundamentally different from transgenic plants”, and that they should be “handled at the regulatory level like traditionally bred plants”.4 On a dedicated website run by Schouten and Jacobsen and supported by Wageningen University5 cisgenesis is described as “a next step in classical breeding for improving crops”. A 'white paper' on the website puts forth the case for deregulating cisgenesis, with the key argument that “plants without foreign DNA should not be regarded as GMOs”. Despite all of these statements however, the Wageningen researchers clearly acknowledge that cisgenesis is genetic modification, both on this website and in public debates.6

Cisgenesis as practiced in the DuRPh project involves the use of a standard genetic engineering technique.7 In fact, two-thirds of the DuRPh potatoes contained marker genes of bacterial origin, and are thus technically transgenic. (The researchers claim that these genes will not be present in the final product.)8

The article accordingly sparked a lively debate in Nature Biotechnology. Two groups of scientists (one of them comprising Dutch plant breeding experts) criticised Schouten and Jacobsen's argumentation, maintaining that cisgenics cannot be regarded as equivalent to traditionally breeding in terms of food and environmental safety.9

Independent Science News added to the discussion, saying “while categorizing transgenes according to their origins may have merit, changes to risk assessment and regulations need to be based on scientific data not semantics”.10 They looked at actual experimental data that do not seem to support claims made by the Wageningen researchers, for instance that products resulting from cisgenesis are equivalent to those resulting from traditional breeding.


Convincing Dutch Government and Parliament

In the political arena, the first step was to convince Dutch political parties that cisgenic potatoes should be treated differently from ‘traditional’ GMOs. The Protestant Orthodox party ChristenUnie, which has a history of critical positioning on GM, seemed like a good starting point. Not only was DuRPh researcher Henk Schouten a party insider, but ChristenUnie was entering a government coalition for the first time in 2007. At a parliamentary roundtable on biotechnology that year organised by a ChristenUnie MP, Schouten represented the private arm of Wageningen University – Plant Research International – and repeated that cisgenesis “is closer to nature and the order of [God's] creation”.11

Nonetheless, the director of the Wageningen Plant Sciences Group, Ernst van den Ende, later denied that the University had undertaken any political lobbying: “We deliver facts and insights. We have nothing to do with decision making.”12 He claimed that if university researchers communicate favourably about cisgenesis, they do so “in their personal capacity”.

So let's have a look at the capacity in which Schouten makes the case that cisgenics should be excluded from GM laws in meetings with EU decision makers. While Wageningen University is not an official member of industry's EU lobby vehicle, the New Breeding Techniques (NBT) Platform,  Schouten represents the Dutch fruit breeding company Inova Fruit, a client of Wageningen's Plant Research International, in that Platform. Inova Fruit, which is owned by several large fruit auctioneers including The Greenery, contracted Wageningen University to develop a cisgenic apple variety.13 In this context, Schouten is listed as an inventor in a patent application by Inova Fruit.14 This dual role leads to situations where Schouten wears two hats: at an important meeting set up by the NBT Platform in 2012, Schouten attended both as a Wageningen University researcher and as a representative of Inova Fruit.

This situation illuminates the active role played by Wageningen University in the lobby for the deregulation of cisgenesis. Wageningen's political priorities appear to be focused on the interests of its private clients, as well on potential future spin-offs and the patent portfolio of the university.

The business case for cisgenic crops

Cisgenic crops have economic appeal in that a specific new trait can be added to an existing variety that has a solid reputation and market position, like Bintje potatoes or Gala apples.15 The novelty of the new trait and/or the resulting variety can then be patented without having to change the original variety name. Growers can then be charged higher prices due to the patents. Patents undermine the rights of plant breeders and farmers to produce new varieties and seeds, and thereby jeopardise agrobiodiversity.

The certitude promoted by industry and Wageningen about the safety of cisgenics did not however go undisputed. When the Dutch RIKILT Institute of Food Safety, which is linked to Wageningen University, was asked in 2010 to assess the risks of cisgenics, it concluded that “there is, from a food and feed safety perspective, no scientific basis for a general reduction of requirements for cisgenic crop plant varieties”.16 IKILT also concluded that the definition of cisgenics is ambiguous in terms of food safety, “as it may not exclude wild relatives that are not part of the human diet so far and that can only be crossed under laboratory conditions”. If that is the case, there is no “history of safe use”, and the safety of the newly introduced nucleotide sequences and protein(s) would have to be assessed.17

In 2012, the European Food Safety Authority (EFSA) issued an opinion on the risks associated with cisgenics.18 The only external expert invited to give his view to the EFSA working group developing this opinion was Evert Jacobsen of the Wageningen DuRPh team. The working group concluded that “similar hazards can be associated with cisgenic and conventionally bred plants”. However, it was added that the possibility of unintended changes still mandated a case-by-case assessment.

In the meantime, Schouten had successfully convinced the ChristenUnie that cisgenesis would not constitute an interference in God's creation. Following the EFSA opinion, a ChristenUnie parliamentarian stated that cisgenesis is “not only safe, but also ethically responsible”,19 and tabled a resolution in the Dutch Parliament calling for the exclusion of cisgenesis from EU GMO laws.20 The resolution cited EFSA’s conclusion that the risks from the technique are comparable to those associated with conventional breeding. The other half of EFSA's conclusion however, calling for a case-by-case assessment, was left out of the resolution text. The resolution was voted in by a majority consisting of centre and right-wing liberal and conservative parties. Left-wing parties voted against the resolution.21

Push for cisgenic potatoes moves to Brussels

From this point on, the EFSA opinion became the Dutch Government's main argument in its push for the deregulation of cisgenics at the EU level. In late 2012, Dutch officials from the Ministry of Environment and the Permanent Representation in Brussels met with Ladislav Miko from the Directorate-General for Health and Food Safety (DG SANCO).22 They conveyed the desire of Dutch researchers and industry “to have some or all new plant breeding techniques out of the scope of the GMO legislation”, and welcomed the EFSA opinion on cisgenics.

Again the following year, both the Dutch Environment Minister23 and the Ministry of Agriculture24 urged the Commission to issue a decision on the new cisgenic techniques. In addition, the Dutch Secretary of State for the Environment told the media that cisgenic crops should go unlabelled, but that a traceability system could guarantee a cisgenic-free organic food sector.25

Around the same time, ChristenUnie MEP Peter van Dalen pushed the issue in a European Parliament report on horticulture. His political group inserted changes favouring a different approval process for cisgenic plants than for GMOs, “so as to recognise that cisgenesis is an accelerated form of conventional plant breeding”.26 The following year, van Dalen prodded the Commission about how and when it intended to act upon this horticulture report.27

The NBT Platform events meanwhile also prominently pushed the case of cisgenesis. (See article 'Biotech lobby’s push for new GMOs to escape regulation'). Schuttelaar & Partners - with offices in Brussels, The Hague and Wageningen - and the lobbyist in charge Edwin Hecker, a former official at the Dutch Ministry of Agriculture, seemed indeed well placed in that respect.

In the meantime, another project promoting a blight-resistant potato had been launched at Wageningen University in 2008. Developed in cooperation with an organic plant breeding institute, this 'Bioimpuls' potato was non-GM and focused on the organic sector. Yet when Wageningen researcher Richard Visser presented the DuRPh project at a December 2015 European Parliament hearing on “new plant breeding techniques”, he failed to even mention this organic potato developed – within the same university – in parallel with the GM one but granted roughly four times fewer financial resources.28

Dutch potato to become Belgian fry?

The Dutch Government has clearly gone out of its way to push cisgenics, both in terms of funding and political lobbying. Thus it was an embarrassing defeat when the flagship GM potato – the project that was designed to secure the competitiveness of the Dutch potato industry – failed to attract sufficient industry investment to continue in the summer of 2015.

If cisgenesis were however to be exempted from EU GM laws and thus escape labelling, the situation could change quickly. A struggle can be expected between the Dutch Government and the Parliament: in 2014, the Parliament adopted a resolution demanding that cisgenic products be labelled even if excluded from GM regulation, in order to guarantee freedom of choice.29 This is precisely what government officials and researchers set out to avoid when they began the campaign for the deregulation of cisgenesis. Consequently, if their deregulation lobby proves successful at the EU level, they will find themselves in a very awkward situation. Proposing to label a product that has just been exempted from the EU GM law will not be a popular move in Brussels, where the Netherlands holds the EU Presidency in the first half of 2016.

In the meantime, the Flemish biotechnology institute VIB has taken over the drive to commercialise the Dutch cisgenic blight resistant potato, aiming to develop a GM version of the Bintje potato that is much used for the famous Belgian fries.30 The VIB has in turn become strikingly vocal with EU decision makers in the bid to have new GM techniques excluded from EU laws. “It is to be hoped”, VIB states, “that the EU will not apply the stringent GMO legislation to the cisgenic blight-resistant potato, otherwise the cisgenic Bintje will face a long authorisation procedure”. (See also 'Biotech lobby's push for new GMOs to espace regulation').

The Dutch GM potatoSo why is the Netherlands so focused on the regulatory status of cisgenesis? In short, the Dutch are hoping that cisgenic genetic engineering can make the Dutch plant breeding sector more competitive. The Netherlands is known for its considerable stake in the seed industry. The Dutch potato sector for example accounts for 60 per cent of global exports in seed potatoes.1 However, fears have been expressed in The Hague that the sector could lose its standing if competitors from other countries are able to use genetic modification, which consumer rejection has ruled out in the Netherlands.2For this reason, the Dutch Government committed public research funding in 2005 to the development of a 'national GM potato'. Ten million euro was made available to Wageningen University to develop a GM potato that is resistant to late blight (Phytophthora infestans). The project – 'Durable Resistance to Phytophthora' (or DuRPh, which means 'dare' in Dutch) – 'stacks' three to five blight-resistant genes from wild varieties of potatoes, and then inserts them into commercial potato varieties.Dutch Government policy is to cap public science funding at 50 per cent of a research project, requiring matching funding from the private sector. Yet in this case the Dutch potato sector refused to invest in the project, and the exceptional decision was taken to entirely finance the R&D of the GM cisgenic potato from public science coffers. A sizeable one-tenth of the DuRPh budget – one million euro – was allocated to communication with stakeholders and the public in order to overcome the anticipated resistance to the project.However, there was an additional obstacle for project sponsors: European GM laws, which play a crucial role in facilitating consumer choice. If classified and labeled as a GMO, rejection by consumers and the potato processing industry would likely stymie the commercial success of the project. Having cisgenesis excluded from GM laws thus became a key objective for the Dutch Government.Cisgenesis vs transgenesis: is the debate scientific or semantic?The term 'cisgenesis' refers to the insertion of genes from the same or closely related species into a recipient plant, in contrast with transgenesis, whereby genes from another species are introduced. Wageningen University plant scientists Evert Jacobsen and Henk Schouten are considered the 'fathers' of cisgenesis; Schouten coined the term in 1999.3Schouten and Jacobsen made their case for cisgenesis in the Nature Biotechnology journal in 2006, stating that “cisgenic plants are fundamentally different from transgenic plants”, and that they should be “handled at the regulatory level like traditionally bred plants”.4 On a dedicated website run by Schouten and Jacobsen and supported by Wageningen University5 cisgenesis is described as “a next step in classical breeding for improving crops”. A 'white paper' on the website puts forth the case for deregulating cisgenesis, with the key argument that “plants without foreign DNA should not be regarded as GMOs”. Despite all of these statements however, the Wageningen researchers clearly acknowledge that cisgenesis is genetic modification, both on this website and in public debates.6Cisgenesis as practiced in the DuRPh project involves the use of a standard genetic engineering technique.7 In fact, two-thirds of the DuRPh potatoes contained marker genes of bacterial origin, and are thus technically transgenic. (The researchers claim that these genes will not be present in the final product.)8The article accordingly sparked a lively debate in Nature Biotechnology. Two groups of scientists (one of them comprising Dutch plant breeding experts) criticised Schouten and Jacobsen's argumentation, maintaining that cisgenics cannot be regarded as equivalent to traditionally breeding in terms of food and environmental safety.9Independent Science News added to the discussion, saying “while categorizing transgenes according to their origins may have merit, changes to risk assessment and regulations need to be based on scientific data not semantics”.10 They looked at actual experimental data that do not seem to support claims made by the Wageningen researchers, for instance that products resulting from cisgenesis are equivalent to those resulting from traditional breeding.Convincing Dutch Government and ParliamentIn the political arena, the first step was to convince Dutch political parties that cisgenic potatoes should be treated differently from ‘traditional’ GMOs. The Protestant Orthodox party ChristenUnie, which has a history of critical positioning on GM, seemed like a good starting point. Not only was DuRPh researcher Henk Schouten a party insider, but ChristenUnie was entering a government coalition for the first time in 2007. At a parliamentary roundtable on biotechnology that year organised by a ChristenUnie MP, Schouten represented the private arm of Wageningen University – Plant Research International – and repeated that cisgenesis “is closer to nature and the order of [God's] creation”.11Nonetheless, the director of the Wageningen Plant Sciences Group, Ernst van den Ende, later denied that the University had undertaken any political lobbying: “We deliver facts and insights. We have nothing to do with decision making.”12 He claimed that if university researchers communicate favourably about cisgenesis, they do so “in their personal capacity”.So let's have a look at the capacity in which Schouten makes the case that cisgenics should be excluded from GM laws in meetings with EU decision makers. While Wageningen University is not an official member of industry's EU lobby vehicle, the New Breeding Techniques (NBT) Platform,  Schouten represents the Dutch fruit breeding company Inova Fruit, a client of Wageningen's Plant Research International, in that Platform. Inova Fruit, which is owned by several large fruit auctioneers including The Greenery, contracted Wageningen University to develop a cisgenic apple variety.13 In this context, Schouten is listed as an inventor in a patent application by Inova Fruit.14 This dual role leads to situations where Schouten wears two hats: at an important meeting set up by the NBT Platform in 2012, Schouten attended both as a Wageningen University researcher and as a representative of Inova Fruit.This situation illuminates the active role played by Wageningen University in the lobby for the deregulation of cisgenesis. Wageningen's political priorities appear to be focused on the interests of its private clients, as well on potential future spin-offs and the patent portfolio of the university.The business case for cisgenic cropsCisgenic crops have economic appeal in that a specific new trait can be added to an existing variety that has a solid reputation and market position, like Bintje potatoes or Gala apples.15 The novelty of the new trait and/or the resulting variety can then be patented without having to change the original variety name. Growers can then be charged higher prices due to the patents. Patents undermine the rights of plant breeders and farmers to produce new varieties and seeds, and thereby jeopardise agrobiodiversity.The certitude promoted by industry and Wageningen about the safety of cisgenics did not however go undisputed. When the Dutch RIKILT Institute of Food Safety, which is linked to Wageningen University, was asked in 2010 to assess the risks of cisgenics, it concluded that “there is, from a food and feed safety perspective, no scientific basis for a general reduction of requirements for cisgenic crop plant varieties”.16 IKILT also concluded that the definition of cisgenics is ambiguous in terms of food safety, “as it may not exclude wild relatives that are not part of the human diet so far and that can only be crossed under laboratory conditions”. If that is the case, there is no “history of safe use”, and the safety of the newly introduced nucleotide sequences and protein(s) would have to be assessed.17In 2012, the European Food Safety Authority (EFSA) issued an opinion on the risks associated with cisgenics.18 The only external expert invited to give his view to the EFSA working group developing this opinion was Evert Jacobsen of the Wageningen DuRPh team. The working group concluded that “similar hazards can be associated with cisgenic and conventionally bred plants”. However, it was added that the possibility of unintended changes still mandated a case-by-case assessment.In the meantime, Schouten had successfully convinced the ChristenUnie that cisgenesis would not constitute an interference in God's creation. Following the EFSA opinion, a ChristenUnie parliamentarian stated that cisgenesis is “not only safe, but also ethically responsible”,19 and tabled a resolution in the Dutch Parliament calling for the exclusion of cisgenesis from EU GMO laws.20 The resolution cited EFSA’s conclusion that the risks from the technique are comparable to those associated with conventional breeding. The other half of EFSA's conclusion however, calling for a case-by-case assessment, was left out of the resolution text. The resolution was voted in by a majority consisting of centre and right-wing liberal and conservative parties. Left-wing parties voted against the resolution.21Push for cisgenic potatoes moves to BrusselsFrom this point on, the EFSA opinion became the Dutch Government's main argument in its push for the deregulation of cisgenics at the EU level. In late 2012, Dutch officials from the Ministry of Environment and the Permanent Representation in Brussels met with Ladislav Miko from the Directorate-General for Health and Food Safety (DG SANCO).22 They conveyed the desire of Dutch researchers and industry “to have some or all new plant breeding techniques out of the scope of the GMO legislation”, and welcomed the EFSA opinion on cisgenics.Again the following year, both the Dutch Environment Minister23 and the Ministry of Agriculture24 urged the Commission to issue a decision on the new cisgenic techniques. In addition, the Dutch Secretary of State for the Environment told the media that cisgenic crops should go unlabelled, but that a traceability system could guarantee a cisgenic-free organic food sector.25Around the same time, ChristenUnie MEP Peter van Dalen pushed the issue in a European Parliament report on horticulture. His political group inserted changes favouring a different approval process for cisgenic plants than for GMOs, “so as to recognise that cisgenesis is an accelerated form of conventional plant breeding”.26 The following year, van Dalen prodded the Commission about how and when it intended to act upon this horticulture report.27The NBT Platform events meanwhile also prominently pushed the case of cisgenesis. (See article 'Biotech lobby’s push for new GMOs to escape regulation'). Schuttelaar & Partners - with offices in Brussels, The Hague and Wageningen - and the lobbyist in charge Edwin Hecker, a former official at the Dutch Ministry of Agriculture, seemed indeed well placed in that respect.In the meantime, another project promoting a blight-resistant potato had been launched at Wageningen University in 2008. Developed in cooperation with an organic plant breeding institute, this 'Bioimpuls' potato was non-GM and focused on the organic sector. Yet when Wageningen researcher Richard Visser presented the DuRPh project at a December 2015 European Parliament hearing on “new plant breeding techniques”, he failed to even mention this organic potato developed – within the same university – in parallel with the GM one but granted roughly four times fewer financial resources.28Dutch potato to become Belgian fry?The Dutch Government has clearly gone out of its way to push cisgenics, both in terms of funding and political lobbying. Thus it was an embarrassing defeat when the flagship GM potato – the project that was designed to secure the competitiveness of the Dutch potato industry – failed to attract sufficient industry investment to continue in the summer of 2015.If cisgenesis were however to be exempted from EU GM laws and thus escape labelling, the situation could change quickly. A struggle can be expected between the Dutch Government and the Parliament: in 2014, the Parliament adopted a resolution demanding that cisgenic products be labelled even if excluded from GM regulation, in order to guarantee freedom of choice.29 This is precisely what government officials and researchers set out to avoid when they began the campaign for the deregulation of cisgenesis. Consequently, if their deregulation lobby proves successful at the EU level, they will find themselves in a very awkward situation. Proposing to label a product that has just been exempted from the EU GM law will not be a popular move in Brussels, where the Netherlands holds the EU Presidency in the first half of 2016.In the meantime, the Flemish biotechnology institute VIB has taken over the drive to commercialise the Dutch cisgenic blight resistant potato, aiming to develop a GM version of the Bintje potato that is much used for the famous Belgian fries.30 The VIB has in turn become strikingly vocal with EU decision makers in the bid to have new GM techniques excluded from EU laws. “It is to be hoped”, VIB states, “that the EU will not apply the stringent GMO legislation to the cisgenic blight-resistant potato, otherwise the cisgenic Bintje will face a long authorisation procedure”. (See also 'Biotech lobby's push for new GMOs to espace regulation'). 1. Snijders, H., et al. De economische kracht van agrofood in Nederland. 2007. 2. US Department of Agriculture. Netherlands Agricultural Biotechnology Annual: Global Agricultural Information Network (GAIN) Report. 2015. 3. NieuweOogst website. Moderne veredeling met een klassiek resultaat. 2010. http://epaper2.penthionstudio.nl/MagazineGewas/epaperarchive/2010/06-19/... 4. Schouten, H.J., et al. Do cisgenic plants warrant less stringent oversight? Correspondence in: Nature Biotechnology 24, 753. 2006. www.nature.com/nbt/journal/v24/n7/full/nbt0706-753.html 5. http://www.cisgenesis.com 6. European Parliament. Hearing on “New Techniques for Plant Breeding”. 1 December 2015. http://www.europarl.europa.eu/committees/en/agri/events.html?id=20151201... 7. DuRPh programme team. Duurzame Resistentie tegen Phytophthora in aardappel – DuRPh halverwege. 2010. http://www.wageningenur.nl/upload_mm/d/4/0/ebfe5a27-72f7-407d-8d15-b0ba8... 8. ASEED Europe. Criticism on DuRPh-project. 11 July 2013. http://aseed.net/en/kritische-vragen-bij-het-durph-project-gentechaardap... 9. Schubert D and Williams D; De Cock Buning T, Lammerts van Bueren E, Haring M, De Vriend H and Struik P. Cisgenic' as a product designation. Correspondence in: Nature Biotechnology 24, pp. 1329-1331. 2006. 10. Wilson A and Latham J. Cisgenic plants: Just Schouten from the Hip? Independent Science News. 23 February 2007. https://www.independentsciencenews.org/health/cisgenic-plants/ 11. Digibron, Kenniscentrum Gereformeerde Gemeente. CU ziet ruimte voor soorteigen gentech. 2 November 2007. http://www.digibron.nl/search/detail/012dc0dbeb18c47021fe0ae6/cu-ziet-ru... 12. Nieuwe Oogst. Wageningen UR ontkent lobby cisgenese. 17 August 2013. http://www.nieuweoogst.nu/scripts/edoris/edoris.dll?tem=LTO_TEXT_VIEW&do... 13. Nieuwe Oogst. Moderne veredeling met een klassiek resultaat. 19 June 2010. http://epaper2.penthionstudio.nl/MagazineGewas/epaperarchive/2010/06-19/.... Schouten was also considering the application of two other cisgenetic techniques: apples with red pulp, and column-shaped trees that would need less pruning and would facilitate harvesting by robots. 14. European Patent Register. WO2014092561 – Gene and method for increasing disease resistance in perennial plants. Filed on 5 December 2013. https://register.epo.org/application?number=EP13808261 15. - Nieuwe Oogst. Moderne veredeling met een klassiek resultaat. 19 June 2010. http://epaper2.penthionstudio.nl/MagazineGewas/epaperarchive/2010/06-19/.... Schouten stressed the economic importance of the cisgenetic technique: desired genes can be ‘built in’ to existing apple varieties.- DuRPh programme team. Duurzame Resistentie tegen Phytophthora in aardappel – DuRPh halverwege. Page 12. 2010. http://www.wageningenur.nl/upload_mm/d/4/0/ebfe5a27-72f7-407d-8d15-b0ba8...- and http://www.vib.be/nl/educatie/Documents/VIB_dossier_%20schimmelresistent... 16. RIKILT Institute of Food Safety. Food and feed safety aspects of cisgenic crop plant varieties. April 2010. 17. It is also stated that the same should apply for conventionally bred plants with such traits from wild relatives. 18. EFSA. Scientific opinion addressing the safety assessment of plants developed using cisgenesis and intragenesis. 2012. http://www.efsa.europa.eu/fr/efsajournal/pub/2561 19. ChristenUnie website. Bijdrage Esmé Wiegman aan het algemeen overleg biotechnologie en kwekersrecht. 5 April 2012. http://www.christenunie.nl/k/nl/news/view/514815/240/bijdrage-esme-wiegm... 20. Tweede Kamer der Staten Generaal. Beleidsnota Biotechnologie. Motie van de leden Ormel en Wiegman – Van Meppelen Scheppink over vrijstelling van cisgenesetechnieken van EU-wet- en regelgeving (27428, nr. 223). 19 April 2012. https://zoek.officielebekendmakingen.nl/kst-27428-223.html 21. Tweede Kamer der Staten Generaal. Stemmingen VAO Biotechnologie en kwekersrecht. 26 April 2012. https://zoek.officielebekendmakingen.nl/h-tk-20112012-82-22.odt 22. - DG SANCO. Steering note for Mr Ladislav Miko at the occasion of a visit by Mr Hugo von Meijenfeldt, Dutch Ministry of the Environment. 13 November 2012.- Dutch Permanent Representation. Email to DG SANCO. 13 November 2012. Obtained through Freedom of Information request by CEO. 23. Dutch Ministry of the Environment. Letter to Health Commissioner Tonio Borg. 18 December 2013. Obtained through Freedom of Information request by CEO. 24. DG SANCO. Steering note for telefphone call with Mr Hans Hoogeveen, Dutch Ministry of Agriculture. 17 December 2013. Obtained through Freedom of Information request by CEO. 25. Boerderij. Atsma: alleen biologisch gegarandeerd cisgenese-vrij. 16 October 2012. http://www.boerderij.nl/Home/Nieuws/2012/10/Atsma-alleen-biologisch-gega... 26. Parltrack. Resolution. Future of Europe's horticulture sector. 2013/2100 (INI). http://parltrack.euwiki.org/dossier/2013/2100%28INI%29 27. DG SANCO. Answer to written question by Mr Peter van Dalen MEP on cisgenesis. 22 April 2014. Obtained through Freedom of Information request by CEO. 28. Personal communication. 29. Tweede Kamer der Staten Generaal. Beleidsnota Biotechnologie. Motie van het lid Van Gerven. 27 May 2014. https://zoek.officielebekendmakingen.nl/kst-27428-275.html 30. VIB. Fact series. Een schimmelresistente aardappel voor België. December 2014. http://www.vib.be/nl/educatie/Documents/VIB_dossier_%20schimmelresistent...
 

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A few weeks after the May coup against Dilma Rousseff by conservative parties backed by the country's largest corporations, Brazil's “interim” government, led by Michel Temer, signed an emergency loan to the State of Rio de Janeiro to help finance infrastructure for the 2016 Olympics. The bailout was conditional to selling off the State's public water supply and sanitation company, the Companhia Estadual de Águas e Esgotos (Cedae). 

When we interviewed City Councillor and chair of Rio’s Special Committee on the Water Crisis Renato Cinco, in December 2015, he was already warning against such privatisation threats and provided important background information on the water situation in Rio.

Never before has a former European Commission official been criticised as much for his post-EU career as ex-Commission president Barroso upon joining infamous US investment bank Goldman Sachs this summer. Citizens are outraged and evidence already points towards a gross violation of the EU Treaty.

Following the high-level appointment of former European Commission President José Manuel Barroso to Goldman Sachs, NGOs have launched a petition demanding stricter rules for ex-EU commissioners’ revolving door moves.

Corporate Europe Observatory's new report 'A spoonful of sugar' illustrates how the sugar lobby undermines existing laws and fights off much-needed measures that are vital for tackling Europe’s looming obesity crisis.

 
 
 
 
 
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The corporate lobby tour